Description :

The covid 19 research virtual issue is a repository for all material published on covid 19 in the journal of clinical pharmacology the virtual issue will be updated as covid 19 related papers are published the journal of clinical pharmacology american college of clinical pharmacology 50th anniversary issue . This international journal is an authoritative source for ground breaking clinical and basic research in immunopharmacology and immunotoxicology. This review outlines the clinical pharmacology characteristics and development challenges for the 6 approved immunomodulatory monoclonal antibodies that target 2 immune checkpoint pathways ipilimumab an anti cytotoxic t lymphocyte antigen 4 antibody and more recently nivolumab and pembrolizumab both anti programmed death 1 . Immunotherapy is the treatment of diseases by activating amplifying or suppressing the bodys natural immune responses while it has the potential for application across all diseases it has made the greatest impact on the management of patients with cancer and autoimmune diseases